Darier =داء داريير Dariers Disease Darier’s disease is usually transmitted in an autosomal dominant pattern. It has been found to be due to mutations in the ATP2A2 gene on chromosome T2, which encodes the sarcoplasmic/endoplasmic reticulum calcium pumping ATPase SERCA2 (206). The gene is 12q23-24.1. In typical cases, there is a more or less […]
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Degos’ Disease – Malignant Atrophic Papulosis =الضمور الحطاطي الخبيث لديغوس Degas Syndrome Degos had initially described a cutaneointestinal syndrome in which distinct skin findings (“drops of porcelain”) were associated with recurrent attacks of abdominal pain that often ended in death from intestinal perforations . The skin lesions of this syndrome arise in crops of asymptomatic, […]
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Demodex folliculitis =التهاب الاجربة الشعرية بالدويدات Rosacea ROSACEA Despite universal recognition, rosacea remains a controversial topic in dermatology, largely because of its uncertain pathophysiology and clinical variation. Practitioners and the public can easily identify the prototypical red face of rosacea; however, confusion arises when photodamage, perioral dermatitis, post-adolescent acne, and topical steroid overuse present […]
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Dermatitis herpetiformis (Duhring’s disease) =التهاب الجلد العقبولي الشكل = داء دورينغ Dermatitis Herpetiformis Dermatitis herpetiform is is an intensely pruritic, chronic recurrent dermatitis that has a slight male predilection. The lesions usually develop in young to middle-aged adults as symmetrical grouped erythematous papulovesicles, vesicles, or crusts . Oral lesions are absent. The elbows, knees, buttocks, […]
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Dermatofibroma =الورم الليفي(الليفوم) الجلدي Dermatofibroma The overlying epidermis is usually acanthotic. Pseudoepitheliomatous hyperplasia and a basaloid proliferation may be noted. The hyperplasia may be caused by the action of fibroblasts on epidermal keratinocytes.23 Basal cell carcinomas occurring upon a dermatofibroma have been reported. Increased pigment may be seen, which may be iron or melanin. […]
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Dermatofibrosarcoma protuberans =الغرن الليفي الجلدي الناشز الحدبي DERMATOFIBROSARCOMA PROTUBERANS Epidemiology Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive dermal and subcutaneous mesenchymal neoplasm that typically occurs during the third and fourth decades of life, although it has been reported in patients from infancy to the ninth decade. DFSP accounts for less than […]
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Dermatomyositis =التهاب الجلد والعضل Dermatomyositis Dermatomyositis manifests as an inflammatory myopathy with characteristic cutaneous findings. In the absence of cutaneous findings, the diagnosis of polymyositis is applied. Cutaneous findings alone, without muscular involvement, have been termed amyopathic dermatomyositis or dermatomyositis sine myositis (. Both dermatomyositis and polymyositis are uncommon diseases that have a similar incidence. Both have two peaks […]
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Dermatophytie =سعفة فطرية OLYMPUS DIGITAL CAMERA Dermatophytie biopsy findings would show spongiosis, parakeratosis (that may alter with orthokeratosis), and a superficial inflammatory infiltrate. Neutrophils may be seen in the stratum corneum, which is a significant diagnostic clue. On occasion, septate branching hyphae are seen in the stratum corneum. Special fungal stains (eg, periodic acid-Schiff, Gomori methenamine silver) […]
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