Ochronosis = التمعر

Ochronosis = التمعر  ALKAPTONURIA      (ochronosis).     Alkaptonuria , or homogentisic acid oxidase (HGO) deficiency, is a rare metabolic disorder. Excessive homogentisic acid (HGA) is excreted in the urine, which often turns dark, and HGA accumulates in connective tissues, including the dermis49 (ochronosis). Epidemiology Alkaptonuria is inherited as an autosomal recessive trait. Pedigrees suggestive […]

Read More

Onchocerciasis = داء كلابية الذنب

Onchocerciasis = داء كلابية الذنب Onchocerciasis Several different skin manifestations can become apparent during the course of onchocerciasis. Onchocercal depigmentation or “leopard skin” is rarely associated with pruritus and is one of the most common skin manifestations of onchocerciasis. Hypopigmented patches with perifollicular spots of normally pigmented skin, typically occur symmetrically on the pretibial area […]

Read More
error: Content is protected !!