Pemphigus Foliaceous =الفقاع الورقي |
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Pemphigus Foliaceus
The characteristic clinical lesions of PF are scaly, crusted erosions, often on an erythematous base. In more localized and early disease, these lesions are usually well demarcated and scattered in a seborrheic distribution, including the face, scalp, and upper trunk . The primary lesions of small flaccid blisters are often inconspicuous and difficult to find. Disease may stay localized for years, or it may rapidly progress to sometimes generalized involvement, resulting in an exfoliative erythroderma . Exposure to sun, heat, or both may exacerbate disease activity. Patients with PF often complain of pain and burning in the skin lesions. In contrast to patients with PV, those with PF only very rarely, if ever, have mucous membrane involvement, even with widespread disease.
The colloquial term for Brazilian endemic pemphigus, fogo selvagem (Portuguese for “wild fire”), takes into account many of the clinical aspects of this disease: the burning feeling of the skin, the exacerbation of disease by the sun, and the crusted lesions that make the patients appear as if they had been burned.
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